Blastocyst Transfer

Blastocyst Transfer

What is Blastocyst Transfer?

Blastocyst transfer is a technique used in IVF that involves transferring the embryo to the woman’s uterus at a more advanced stage of development. Instead of transferring the embryo a few days after fertilization, blastocyst transfer waits until the embryo has developed for 5-6 days in the lab, reaching the blastocyst stage. This is important because the blastocyst stage is when the embryo would naturally enter the uterus and begin to implant in a natural pregnancy. Growing the embryos longer in the lab allows doctors to better see which ones are the healthiest and most likely to implant, potentially increasing the chances of a successful pregnancy and sometimes reducing the risk of multiple births. However, not all embryos make it to the blastocyst stage, and your doctor will determine if this technique is right for you.

What is the procedure for Blastocyst Transfer?

he blastocyst transfer procedure is similar to a traditional embryo transfer, but it involves embryos that have developed for a longer period in the lab. Here’s a breakdown of the steps:

  1. Embryo Preparation: The embryologist selects the healthiest and most viable blastocysts for transfer. These embryos have been developing in the lab for 5-6 days after fertilization.   

  2. Catheter Loading: The chosen blastocysts are carefully loaded into a thin, flexible catheter.   

  3. Patient Preparation: The woman lies on an examination table, similar to a pelvic exam. A speculum is inserted into the vagina to hold it open, allowing the doctor to visualize the cervix.   

  4. Catheter Insertion: The catheter containing the blastocysts is gently passed through the cervix and into the uterus.

  5. Blastocyst Release: The blastocysts are carefully released from the catheter into the uterine cavity.

  6. Catheter Removal: The catheter is gently removed.

  7. Recovery: After the transfer, the woman typically rests for a short period of time. Specific instructions for post-transfer care will be provided by the clinic.

Need IVF Consultation

24 Hour Ready

Toll Free Number

Book Appointment

Call Us Today for Consultation

Advanced IVF Treatment with Expert Care

FAQ

Frequently Ask Questions.

Blastocyst transfer is a type of IVF where embryos are grown in a lab for 5-6 days until they reach the blastocyst stage, a more developed form. This allows for better selection of the healthiest embryos for transfer, potentially increasing implantation rates. These selected blastocysts are then transferred to the woman's uterus, similar to a traditional embryo transfer.

  • Previous IVF/ICSI Failures: Recommended for couples with prior unsuccessful IVF or ICSI attempts despite good egg quality. Blastocyst culture allows for observation of embryo development between days 3 and 6, potentially revealing developmental issues.
  • Elective Single Embryo Transfer (eSET): Advantageous for couples pursuing eSET, as Day 5 blastocyst transfer increases conception likelihood compared to Day 3 transfers.
  • Preimplantation Genetic Diagnosis (PGD): Used in conjunction with PGD. Blastocyst culture allows for embryo biopsy (removal of cells for genetic analysis) and selection of healthy embryos for transfer.
  • Multiple Healthy Day 3 Embryos: Recommended when several healthy embryos are available on day 3. Extended culture allows selection of the most viable embryo(s) for implantation, reducing the number of embryos needed for transfer and thus the risk of multiple pregnancies.

The blastocyst transfer procedure is very similar to a traditional embryo transfer, but the embryos being transferred are at a more advanced stage of development. Here's a step-by-step breakdown:

  1. Embryo Preparation: In the lab, the embryologist selects the most viable and healthy blastocysts for transfer. These are the embryos that have developed for 5-6 days after fertilization.

  2. Catheter Loading: The chosen blastocysts are carefully loaded into a thin, flexible catheter. This catheter is specifically designed for embryo transfer.

  3. Patient Preparation: The woman lies on an examination table, similar to the position for a pelvic exam or Pap smear. A speculum is inserted into the vagina to gently hold it open, making the cervix visible.

  4. Catheter Insertion: The catheter, containing the blastocysts, is carefully and gently passed through the cervix and into the uterus. The doctor or embryologist performing the procedure will carefully guide the catheter to the optimal location within the uterine cavity.

  5. Blastocyst Release: Once the catheter is in the correct position, the blastocysts are gently released from the catheter into the uterus.

  6. Catheter Removal: The catheter is then carefully and gently removed.

  7. Recovery: After the transfer, the woman will typically rest for a short period at the clinic or fertility center. She'll receive specific instructions for post-transfer care, including any medications to take and activity restrictions.

In a fresh embryo transfer, the entire IVF process, from ovarian stimulation and egg retrieval to fertilization, embryo culture, and transfer, is completed in one cycle. A frozen transfer, on the other hand, uses previously frozen embryos, so only the uterine preparation and transfer steps are needed.

  • Embryo Transfer (Day 3):

    • Performed on the third day after fertilization.
    • Embryo is not yet at the stage for natural implantation.
    • Multiple embryos (2-3) may be transferred to increase the chance of at least one implanting.

 

  • Blastocyst Transfer (Day 5-6):

    • Embryo is allowed to develop for two more days, reaching the blastocyst stage.
    • Only the most viable embryos typically reach this stage (natural selection).
    • Implantation occurs soon after transfer.
    • Usually only one blastocyst is transferred due to the higher likelihood of implantation.
error: Content is protected !!